Comments on IVF Authority: DQ alpha/HLA Sharing: Does It Always Lead To Repro...

I would need to see the entire panel to comment. I...

2010-10-21T20:42:07.936-07:00

I would need to see the entire panel to comment. I would also need to know where the testing was done.

Geoff Sher

Dear Dr. Sher, My husband and I have recently don...

2010-10-21T14:42:56.207-07:00

Dear Dr. Sher,

My husband and I have recently done HLA genotype panel test and would like to know if all the results have to match to confirm male/female do match 100%.
i.e if HLA-DRB1 has some similarity (13,13, DRB3 present- for female and 13,14,DRB3 present). How can one interpret these results?

Thank you,

Aline

You are most welcome! Geoff Sher

2009-10-27T14:18:14.220-07:00

You are most welcome!

Geoff Sher

Thank you Dr. Sher!

2009-10-27T13:48:46.158-07:00

Thank you Dr. Sher!

Your LAD's will be negative since you are test...

2009-10-27T10:32:00.859-07:00

Your LAD's will be negative since you are testing them against a new donor. They are also irrelevant. There is thus no point in doing them in my opinion.

It is unlikely you have a DQa/HLA match with the sperm donor, but in case you do, perhaps you might consider getting his and your DQa/HLA compared and most importantly, getting your NK cell activity (NKa) tested by way of the K-562 target cell test.

Good luck!

Geoff Sher

Dr. Sher, I am using anonymous donor sperm and am...

2009-10-27T10:24:22.399-07:00

Dr. Sher,

I am using anonymous donor sperm and am undergoing IVF. As I cannot test my LADs with the donor, is there anything that can be done to protect the embryos once they have been transferred?

Thank you!